2-Butenoic acid, 4,4,4-trifluoro-3-(methylamino)-, ethyl ester, (2Z)- - Names and Identifiers
Name | ethyl (2Z)-4,4,4-trifluoro-3-(methylamino)but-2-enoate
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Synonyms | ethyl (2Z)-4,4,4-trifluoro-3-(methylamino)but-2-enoate 2-Butenoic acid, 4,4,4-trifluoro-3-(methylamino)-, ethyl ester, (2Z)- Ethyl 4,4,4-trifluoro-3-(methylamino)but-2-enoate
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CAS | 507448-65-9
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EINECS | 801-277-8 |
2-Butenoic acid, 4,4,4-trifluoro-3-(methylamino)-, ethyl ester, (2Z)- - Physico-chemical Properties
Molecular Formula | C7H10F3NO2
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Molar Mass | 197.15 |
Density | 1.207g/cm3 at 20℃ |
Boling Point | 171℃ at 101.325kPa |
Vapor Presure | 1-1.6hPa at 20-25℃ |
2-Butenoic acid, 4,4,4-trifluoro-3-(methylamino)-, ethyl ester, (2Z)- - Introduction
ethyl (2Z)-4,4,4-trifluoro-3-(methylamino)but-2-enoate is a chemical compound commonly referred to as ethyl (Z)-trifluoro-3-(methylamino)crotonate.
Nature:
-Appearance: colorless liquid
-molecular formula: C6H7F3NO2
-Molecular weight: 189.12g/mol
-Boiling Point: 84-86 degrees Celsius
-Melting Point: No melting point data
-density: 1.273 g/cm
-Solubility: Soluble in ethanol, chloroform and Ether solvents, insoluble in water.
Use:
-As an important intermediate in organic synthesis, it can be used to synthesize different types of drugs, pesticides and surfactants.
-For the synthesis of biologically active compounds, such as biological pesticides, pesticides, etc.
Preparation Method:
Ethyl (2Z)-4,4,4-trifluoro-3-(methylamino)but-2-enoate is generally prepared by the following steps:
1.3-chloropropene reacts with P-trifluoromethylaniline to generate 3-(trifluoromethyl) benzylamine.
2. Condensation of 3-(trifluoromethyl) benzylamine with hydrofluoric acid to produce 2-trifluoromethylbenzylamine.
3. 2-trifluoromethylbenzylamine reacts with ethyl chloroacetate under alkaline conditions to generate ethyl (2Z)-4,4,4-trifluoro-3-(methylamino)but-2-enoate.
Safety Information:
- ethy1 (2Z)-4,4,4-trifluoro-3-(methylamino)but-2-enoate is a chemical. Pay attention to safe operation and avoid contact with skin and eyes.
-This compound may be harmful to health, potentially toxic and dangerous.
-During use, use appropriate protective equipment, such as gloves, goggles and protective clothing.
-Proper laboratory safety procedures should be followed when storing and handling this compound.
Last Update:2024-04-09 02:00:40